Hepatoprotective and immunomodulatory properties of Tinospora cordifolia in CCl4 intoxicated mature albino rats.
نویسندگان
چکیده
منابع مشابه
Effect of aqueous extract of Tinospora cordifolia on functions of peritoneal macrophages isolated from CCl4 intoxicated male albino mice
BACKGROUND The current practice of ingesting phytochemicals for supporting the immune system or fighting infections is based on centuries-old tradition. Macrophages are involved at all the stages of an immune response. The present study focuses on the immunostimulant properties of Tinospora cordifolia extract that are exerted on circulating macrophages isolated from CCl(4) (0.5 ml/kg body weigh...
متن کاملHepatoprotective and Antioxidant Activities of Combination of Cinnamomum zeylanicum and Zingiber officinale in CCl4-intoxicated Rats
Introduction: Liver is the most important organ of drugs and xenobiotics metabolism and any damage to the liver is associated with dysfunction of this organ. This study was carried out to find the possible additive effect of the co-administration of Cinnamomum zeylanicum (cinnamon) and Zingiber officinale (ginger) extracts on carbon tetrachloride (CCl4</s...
متن کاملPhytochemical analysis and hepatoprotective properties of Tinospora cordifolia against carbon tetrachloride-induced hepatic damage in rats
The present study was conducted to evaluate the hepatoprotective activity of different extracts of Tinospora cordifolia against carbon tetrachloride (CCl4) induced liver damage in rats. The pet ether, ethanol and aqueous extracts of various parts of the plant such as leaf, stem and root were tested at the dose of 200mg/kg body weight orally using Wistar albino rats and Silymarin was given as re...
متن کاملHepatoprotective and immunomodulatory properties of aqueous extract of Curcuma longa in carbon tetra chloride intoxicated Swiss albino mice.
OBJECTIVE To evaluate the hepatoprotective and immunotherapeutic effects of aqueous extract of turmeric rhizome in CCl4 intoxicated Swiss albino mice. METHODS First group of mice (n=5) received CCl4 treatment at a dose of 0.5 mL/kg bw (i.p.) for 7 days. Second group was fed orally the aqueous extract of turmeric at a dose of 50 mg/kg bw for 15 days. The third group was given both the turmeric...
متن کاملImmunomodulatory effects of Tinospora cordifolia (Guduchi) on macrophage activation
Macrophages are the first line of defense and constitute important participants in the bi-directional interaction between innate and specific immunity. Macrophages are in a quiescent form and are activated when given a stimulus. In the present study, we have used Tinospora cordifolia, commonly known as Guduchi, to see its effect on macrophage activation. The direct drug treatment to J774A cells...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 2002
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.27.139